30.1.77 Goldman

Function

E=\frac{RT}F\ln \left( \frac{\left[ K\right] _0+b\left[ Na\right] _0}{\left[ K\right] _i+b\left[ Na\right] _i}\right)

Where \left[ K\right] _0 as x, E as y.

R=8.314,F=96485,b=P_{Na}/P_k.

Brief Description

Goldman-Hodgkin-Katz equation for use in cell membrane physiology.

Sample Curve

CFF Image232.gif

Parameters

Number: 5

Names: b, Nao, Nai, Ki, T

Meanings:

b = Relative permeabilities of Na to K,

Nao = Concentraion of Na ions outside,

Nai = Concentraion of Na ions inside,

Ki = Concentraion of K ions inside,

T = Temperature (in Kelvin).

Lower Bounds: Nao >= 0.0, Nai >= 0.0, Ki >= 0.0, T > 0.0.

Upper Bounds: none

Note:

In most cases, only b is set as vary, while all other are should be specified and fixed.

Script Access

nlf_goldman(x, b, Nao, Nai, Ki, T )

Function File

FITFUNC\GOLDMAN.FDF

Category

Electrophysiology