28.1.119 OneSiteComp

Function

y=A_2+\frac{A_1-A_2}{1+10^{\left( x-\log x_0\right) }}

Brief Description

One Site Competition curve. Dose-response curve with Hill slope equal to -1.

Sample Curve

CFF Image340.jpg

Parameters

Number: 3

Names: A1, A2, log(x0)

Meanings: A1 = top asymptote, A2 = bottom asymptote, log(x0) = center

Lower Bounds: none

Upper Bounds: none

Derived Parameters

The span: Span=abs(A1-A2)

The concentration at half response: EC50=10^(logx0)

Script Access

nlf_competition1(x,A1,A2,LOGx0)

Function File

FITFUNC\COMP1.FDF

Category

Pharmacology