28.1.9 BiDoseResp

Function

y=A1+(A2-A1)\left[\frac{p}{1+10^{(LOGx01-x)h1}}+\frac{1-p}{1+10^{(LOGx02-x)h2}}\right]

Brief Description

Biphasic Dose Response Function.

Sample Curve

BiDoseResp.png

Parameters

Number: 7

Names: A1, A2, LOGx01, LOGx02, h1, h2, p

Meanings: A1 = Bottom, A2 = Top, LOGx01 = 1st EC50, LOGx02 = 2nd EC50, h1 = slope1, h2 = slope2, p = proportion

Lower Bounds: none

Upper Bounds: none

Derived Parameters

The span:

Span=abs(A1-A2)

The concentration at half response:

EC50_1=10^(LOGx01)

EC50_2=10^(LOGx02)

Script Access

nlf_BiDoseResp(x,A1,A2,LOGx01,LOGx02,h1,h2,p)

Function File

FITFUNC\BIDOSERESP.FDF

Category

Growth/Sigmoidal